Cart summary

You have no items in your shopping cart.

APOL1-IN-2

SKU: orb2814692

Description

APOL1-IN-2 (Compound 467) is a potent small-molecule inhibitor of apolipoprotein L1 (APOL1). It demonstrates efficacy in vitro by protecting HEK293 cells and killing trypanosomes, with low nanomolar EC50 values against various APOL1 variants (G0, G1, G2), supporting research into kidney disease and parasitology.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2956781-84-1
MW595.01
FormulaC28H30ClF3N4O5
SMILESO=C1C2(C=3C(N1)=CC=C(Cl)C3)CCN(CCOC=4C=C5C(=C(C(F)(F)F)C4)N(C(=O)N5CO)[C@H]6C[C@@](C)(O)C6)CC2
TargetApolipoprotein

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

APOL1-IN-2 (orb2814692)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%