Antiproliferative agent-49

SKU: orb3133792

Description

Antiproliferative agent-49 (Compound 5a) is an EGFR-TK inhibitor with an IC50 of 0.09 μM and serves as an antiproliferative agent. It exhibits significant activity against HER3 and HER4, with IC50 values of 0.18 and 0.37 µM, respectively. Additionally, Antiproliferative agent-49 triggers the mitochondrial apoptotic pathway and enhances ROS accumulation.

Images & Validation

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Key Properties

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Formula	C₂₂H₁₈N₂O₂S
Target	EGFR,Apoptosis

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

EGFR,Apoptosis

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