Anti-NASH agent 1

• Catalog Number: orb1944258
• Category: Small Molecules
• Description: Anti-NASH Agent 1 (Compound 3d), derived from Elafibranor, serves as a strong PPAR-α/δ agonist aimed at treating nonalcoholic steatohepatitis (NASH). At dosages of 3-10 mg/kg over four weeks, this compound ameliorates hyperlipidemia, liver fat degeneration, and inflammation in a methionine-choline deficiency (MCD)-induced NASH mouse model, exhibiting minimal hepatotoxicity while providing substantial hepatic protection [1].
• Purity: 98.00%
• MW: 423.54
• Biological Activity: Anti-NASH Agent 1 (Compound 3d), derived from Elafibranor, serves as a strong PPAR-α/δ agonist aimed at treating nonalcoholic steatohepatitis (NASH). At dosages of 3-10 mg/kg over four weeks, this compound ameliorates hyperlipidemia, liver fat degeneration, and inflammation in a methionine-choline deficiency (MCD)-induced NASH mouse model, exhibiting minimal hepatotoxicity while providing substantial hepatic protection [1].
• CAS Number: 2409685-41-0
• Formula: C₂₆H₃₃NO₄
• SMILES: O(C(C(OC(C)(C)C)=O)(C)C)C1=C(C)C=C(C=CC(=O)C2=CC=C(NC)C=C2)C=C1C
• Storage: -20°C
• Note: For research use only