Anti-NASH agent 1

SKU: orb1944258

Description

Anti-NASH Agent 1 (Compound 3d) is a potent dual PPAR-α/δ agonist derived from Elafibranor. In an MCD diet-induced mouse model of NASH, it significantly reduced hepatic steatosis, inflammation, and hyperlipidemia at doses of 3-10 mg/kg over four weeks, demonstrating hepatoprotective effects with minimal toxicity.

Research Area

Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 2409685-41-0
• MW: 423.54
• Formula: C₂₆H₃₃NO₄
• SMILES: O(C(C(OC(C)(C)C)=O)(C)C)C1=C(C)C=C(C=CC(=O)C2=CC=C(NC)C=C2)C=C1C
• Target: PPAR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172908345