Anti-Collagen Type IV Antibody

SKU: orb1675214

Description

Anti-Collagen Type IV Antibody is designed for detection of collagen IV protein expressing tissue or lysates. Collagen IV is found in the basal lamina and a constituent of the basement membrane which has a role in supporting structure. Disruptions or complete absent of basement membrane may be indicative of upregulation of matrix metalloproteinases secreted by cancer cells. The loss of structure integrity of the basement membrane is associated with stages of invasive cancers.

Research Area

Musculoskeletal & Connective Tissue Research

Images & Validation

• Tested Applications: ELISA, IHC
• Reactivity: Human
• Application Notes:
  1:50-1:200

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: IHC549
• Immunogen: Recombinant Protein
• Purity: Purified
• Purification: Purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Tris Buffer, pH 7.3 - 7.7, with 1% rAlbumin and <0.1% Sodium Azide
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only