Anle138b-F105

SKU: orb2646117

Description

Anle138b-F105 is a potent AUTOTAC (autophagy-targeting chimera) with a DC50 of 3 nM, inducing lysosomal degradation of the tauP301L mutant. This small molecule facilitates the study of targeted protein degradation in models of tauopathy, applicable in both cellular and in vivo research.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2941386-44-1
• MW: 624.7
• Formula: C₃₆H₃₇FN₄O₅
• SMILES: FC1=CC=C(C=C1)COC2=CC=CC(=C2)CNCCOCCOCCNC3=CC=CC(=C3)C4=CC(=NN4)C=5C=CC=6OCOC6C5
• Target: AUTACs,Autophagy

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

151052025