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Catalog Number | orb1307084 |
---|---|
Category | Small Molecules |
Description | Anacetrapib |
CAS Number | 875446-37-0 |
Purity | 99.62% |
MW | 637.51 |
SMILES | C(C1=C(C=CC(C(F)(F)F)=C1)C2=C(OC)C=C(F)C(C(C)C)=C2)N3[C@@H](C)[C@H](OC3=O)C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4 |
Formula | C30H25F10NO3 |
Biological Activity | Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL thereby, producing an increase in serum HDL-cholesterol levels and a decrease in serum LDL-cholesterol levels. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
[875446-37-0] | |
637.5084 | |
C30H25F10NO3 |
> 98% (HPLC) | |
875446-37-0 |
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