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Amsilarotene
Catalog Number: orb1306403
| Catalog Number | orb1306403 |
|---|---|
| Category | Small Molecules |
| Description | Amsilarotene |
| Purity | 99.27% |
| MW | 385.6 |
| Biological Activity | Amsilarotene (TAC101) inhibits the phosphorylation of retinoblastoma gene product (RB) and increases the presence of 2 cyclin-dependent kinases (CDK) inhibitors resulting in cell cycle arrest. This agent also causes a cytotoxic decline in the thymidylate synthase and cyclin A expression. |
| CAS Number | 125973-56-0 |
| Formula | C20H27NO3Si2 |
| SMILES | C[Si](C)(C)c1cc(cc(c1)[Si](C)(C)C)C(=O)Nc1ccc(cc1)C(O)=O |
| Storage | -20°C |
| Note | For research use only |
Amsilarotene [orb1940452]
> 98% (HPLC)
125973-56-0
385.6
C20H27NO3Si2
25 mg, 5 mg, 10 mg, 50 mg, 100 mg, 1 g, 500 mg, 200 mg
