AMPK activator 15

SKU: orb2802341

Description

AP39 Prodrug 1 (M1) is a mitochondria-targeted hydrogen sulfide donor. It triggers mild, ROS-mediated mitochondrial uncoupling in hepatocytes, leading to AMPK activation and protection against palmitic acid-induced steatosis in vitro, making it a tool for studying metabolic liver disease.

Research Area

Epigenetics & Chromatin, Metabolism Research, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 3119328-78-5
• MW: 1004.92
• Formula: C₅₃H₅₁BrNO₁₀PS
• SMILES: O=C1OC2=CC(OCC3=CC(OCCCC[P+](C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)=CC=C3[N+]([O-])=O)=CC=C2C=C1COC(OC7=C(C(C)(C)CC(S)=O)C(C)=CC(C)=C7)=O.[Br-]
• Target: AMPK,Mitochondrial Metabolism,E1/E2/E3 Enzyme

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176419282