Ammonium formate

SKU: orb1221143

Description

Formic acid is the simplest carboxylic acid. Formate is an intermediate in normal metabolism. It is responsible for both metabolic acidosis and disrupting mitochondrial electron transport and energy production by inhibiting cytochrome oxidase activity the terminal electron acceptor of the electron transport chain. Cell death from cytochrome oxidase inhibition by formate is believed to result partly from depletion of ATP reducing energy concentrations so that essential cell functions cannot be maintained. Furthermore inhibition of cytochrome oxidase by formate may also cause cell death by increased production of cytotoxic reactive oxygen species (ROS) secondary to the blockade of the electron transport chain.

Key Properties

• CAS Number: 540-69-2
• MW: 63.06
• Purity: >98% (HPLC)
• Formula: CH₅NO₂
• SMILES: [NH4+].[O-]C=O
• Target: Others
• Solubility: DMSO:200 mM

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Formic acid ammonium salt

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