Alosetron hydrochloride

SKU: orb1305359

Description

Alosetron hydrochloride is a selective 5-HT3 receptor antagonist that blocks serotonin's action in the peripheral nervous system. It is used in research to study visceral pain, gastrointestinal motility, and secretion, with applications in both in vitro binding assays and in vivo models of irritable bowel syndrome.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 122852-69-1
• MW: 330.81
• Purity: 99.90%
• Formula: C₁₇H₁₉ClN₄O
• SMILES: Cl.Cc1nc[nH]c1CN1CCc2c(C1=O)c1ccccc1n2C
• Target: 5-HT Receptor
• Solubility: DMSO:8.57 mg/mL (25.91 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

nociceptive, inhibit, Lotronex, Inhibitor, GR68755, GR-68755, GR 68755, GR 68755C, GR 68755X, 5-HT3, 5-HT Receptor, Alosetron, Alosetron Hydrochloride, Alosetron hydrochloride, 5-hydroxytryptamine Receptor, 5HTReceptor, 5HT Receptor, depolarization, colitis, selective, Serotonin Receptor, visceral

Compound Identifiers

PubChem CID

60758