ALK5-IN-82

SKU: orb2665039

Description

ALK5-IN-82 is a potent and selective ALK5 inhibitor (IC50 = 9.1 nM) that suppresses TGF-β-induced fibrotic markers like α-SMA and collagen I in HUVECs. It is a valuable research tool for studying cardiac fibrosis mechanisms in both cellular and animal models.

Research Area

Cell Biology

Key Properties

• CAS Number: 3001361-04-9
• MW: 429.50
• Formula: C₂₂H₁₉N₇OS
• SMILES: O=C(NCC1=NC(C2=NC(=CC=C2)C)=C(N1)C=3C=CC4=NC=NN4C3)CC=5SC=CC5
• Target: Others,TGF-beta/Smad

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172638525