[Ala2] Endothelin-3, human

SKU: orb1981140

Description

[Ala2] Endothelin-3, human is a linear analog of the vasoactive peptide ET-3, where alanine residues replace cysteines. This modified peptide is used in research to study endothelial cell migration and vascular biology in vitro, serving as a tool to investigate ET-3's paracrine signaling mechanisms without disulfide bonds.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: Endothelin Receptor
• CAS Number: 2243207-08-9
• MW: 2613.02
• Formula: C₁₂₀H₁₆₆N₂₆O₃₂S₄
• SMILES: C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC(=O)[C@H]2NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](CC4=CC=C(O)C=C4)NC(=O)[C@H]([C@H](C)C)NC(=O)[C@]5(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC6=CC=C(O)C=C6)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CC7=CC=CC=C7)NC(=O)[C@@](NC(=O)[C@H](C)NC(=O)[C@@H](N)CSSC2)(CSSC5)[H])[H])[H])=O)CC(C)C)=O)CC(O)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)C(O)=O)C=8C=9C(NC8)=CC=CC9

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176418822