Adonixanthin

SKU: orb3141983

Description

Adonixanthin ((3S,3'R)-Adonixanthin) is a carotenoid that acts as an orally active antioxidant and anticancer agent. It demonstrates the ability to inhibit the proliferation and migration of glioblastoma cells and provides cellular protection against various injuries, suppressing increased reactive oxygen species (ROS) production. Adonixanthin safeguards cells from photo-induced damage through antioxidative responses and Nrf2 activation. It can halt glioblastoma progression and improve blood-brain barrier permeability in autologous intracerebral hemorrhage (ICH) models. This compound is applicable in research related to glioblastoma (GBM) and intracerebral hemorrhage (ICH).

Research Area

Immunology & Inflammation, Metabolism Research, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 4418-73-9
• MW: 582.86
• Formula: C₄₀H₅₄O₃
• SMILES: C(=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C=1C(C)(C)C[C@H](O)CC1C)\C)\C)/C)/C)\C=2C(C)(C)C[C@H](O)C(=O)C2C
• Target: NADPH,Akt,ROS,ERK,p38 MAPK,Nrf2,MMP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

NADPH,Akt,ROS,ERK,p38 MAPK,Nrf2,MMP