Aderamastat

SKU: orb1941603

Description

Aderamastat (FP-025) is an orally bioavailable, selective inhibitor of matrix metalloproteinase 12 (MMP-12). This small molecule research compound is used to investigate MMP-12's role in respiratory pathologies, including allergic asthma, COPD, and pulmonary fibrosis, in both in vitro and in vivo preclinical models.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 877176-23-3
• MW: 394.44
• Purity: 99.35%
• Formula: C₂₁H₁₈N₂O₄S
• SMILES: O=C1NC(=O)C(N1)C=2OC=CC2SC3=CC=C(OCC=4C=CC=C(C4)C)C=C3
• Target: MMP
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.37 mM);DMSO:80 mg/mL (202.82 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

FP-003, FP-025, MMP-12

Compound Identifiers

PubChem CID

67177374