Adaptaquin

SKU: orb1306118

Description

Adaptaquin is a small molecule inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH). It is used in research to stabilize HIF-α, making it a valuable tool for studying cellular responses to hypoxia in both in vitro and in vivo experimental models.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research

Key Properties

• CAS Number: 385786-48-1
• MW: 377.82
• Purity: 99.75% (May vary between batches)
• Formula: C₂₁H₁₆ClN₃O₂
• SMILES: Oc1cccnc1NC(c1ccc(Cl)cc1)c1ccc2cccnc2c1O
• Target: ROS,HIF,HIF/HIF Prolyl-Hydroxylase
• Solubility: DMSO:55 mg/mL (145.57 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Adaptaquin, Inhibitor, Hypoxia-inducible factors, HIF-PH, HIF-PHD2, HIFs, HIF/HIF Prolyl-Hydroxylase, inhibit, mitochondrial, peroxidation

Compound Identifiers

PubChem CID

3740671