AD16

SKU: orb2564533

Description

AD16 (Acetamide) is a small molecule inhibitor of the LINE-1 retrotransposon endonuclease (IC50 = 4.7 µM). It effectively reduces LINE-1 retrotransposition in cellular models, including senescent cells, thereby alleviating associated genomic instability and inflammatory responses in research applications.

Research Area

Cell Biology

Key Properties

• CAS Number: 311315-04-5
• MW: 616.64
• Formula: C₂₄H₂₀N₁₄O₃S₂
• SMILES: O=C(NC1=CC=C2OC(=NC2=C1)C3=CC=C(C=C3)CC(=O)CSC4=NN=C5N4N=CN5N)CSC6=NN=C7N6N=CN7N
• Target: Endonuclease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

16761095