Acetyl-L-carnitine

SKU: orb1701262

Description

Acetyl-L-carnitine

Research Area

Metabolism Research

Key Properties

• CAS Number: 3040-38-8
• MW: 203.24
• Purity: 100.00%
• Formula: C₉H₁₇NO₄
• SMILES: CC(=O)OC(CC([O-])=O)C[N+](C)(C)C
• Target: Endogenous Metabolite
• Solubility: DMSO:2.04 mg/mL (10.04 mM);H2O:2.04 mg/mL (10.04 mM)

Bioactivity

• In Vivo:
  Three different paradigms were used to deliver Acetyl L-carnitine (ALCAR) to aging Fischer 344/NHsd rats. Rats in each condition had their hearing evaluated by auditory brainstem responses before, during, and after treatment. First, 24-month-old rats were given ALCAR (100 mg/kg dissolved 25 mg/ml in saline) by IP injection daily for one month. Second, 18-month-old rats were given ALCAR (100 mg/kg) by oral gavage for 90 days. Third, 15-month-old rats were given ALCAR (100 mg/kg) by oral gavage for 90 days. Control rats in each condition received saline by i.p. injection or gavage. The current study does not provide evidence that age-related hearing loss in the Fischer 344/NHsd rat can be altered with systemic administration of ALCAR.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

RO447190, RO-447190, RO 447190, LAC, L-Acetylcarnitine, EndogenousMetabolite, Endogenous Metabolite, L-O-Acetylcarnitine, Acetyl L carnitine, Acetyl-L-carnitine, ALCAR

Compound Identifiers

PubChem CID

1