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ABP688

SKU: orb1701288

Description

ABP688 is a potent and selective non-competitive mGluR5 antagonist with a Ki of 1.7 nM. It serves as a valuable PET tracer for clinical neuroimaging, enabling in vivo quantification of mGluR5 receptor availability in research on neurological and psychiatric disorders.

Research Area

Neuroscience

Images & Validation

Key Properties

CAS Number924298-51-1
MW240.3
Purity97.85% (May vary between batches)
FormulaC15H16N2O
SMILESC(#CC=1N=C(C)C=CC1)C2=CC(=NOC)CCC2
TargetGluR
SolubilityDMSO:2.45 mg/mL (10.2 mM)

Bioactivity

Target IC50
mGluR5 (human):1.7 nM (Ki)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

mGluR5, ABP-688, ABP688, ABP 688

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Key Properties

No computed properties available.

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Protocol Information

ABP688 (orb1701288)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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Available Sizes

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1 ml x 5 mM (in DMSO)
$ 70.00
10 mg
$ 80.00
25 mg
$ 120.00
50 mg
$ 170.00
DispatchUsually dispatched within 3-5 working days
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