Abd110

SKU: orb2567127

Description

Abd110 (compound 42i) is a PROTAC molecule derived from lenalidomide that selectively degrades ATR kinase. It effectively reduces both total and phosphorylated ATR levels without affecting ATM or DNA-PKcs, making it a valuable tool for studying ATR's role in DNA damage response pathways in cellular and biochemical assays.

Research Area

Molecular Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 3021581-79-0
• MW: 790.89
• Formula: C₄₁H₄₂N₈O₇S
• SMILES: O=C(NC=1C=CC=CC1)C=2N=C(C=NC2N)C3=CC=C(C=C3)S(=O)(=O)NCCCCCC(=O)NCCCC#CC4=CC=CC=5C(=O)N(CC45)C6C(=O)NC(=O)CC6
• Target: ATM/ATR,PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

170836274