Cart summary

You have no items in your shopping cart.

AB-680

SKU: orb1310029

Description

AB-680

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number2105904-82-1
MW580.82
Purity97.98%
FormulaC20H24ClFN4O9P2
SMILESN([C@@H](C)C1=C(F)C=CC=C1)C2=C3C(N(N=C3)[C@@H]4O[C@H](COP(CP(=O)(O)O)(=O)O)[C@@H](O)[C@H]4O)=NC(Cl)=C2
TargetCD73
SolubilityDMSO:150 mg/mL (258.26 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.61 mM)

Bioactivity

Target IC50
CD73:4.9 pM (ki;human)|CD73:43 pM (Soluble hCD73)
In Vitro
AB-680 inhibits soluble hCD73 (IC50: 0.043 nM), also inhibits hCD73 in CHO cells, suppresses CD73 in human, mouse CD8+ T Cells and hPBMC, with IC50s of 0.070, 0.008, 0.66 and 0.011 nM, respectively.

Storage & Handling

Storagestore at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CD73, AB 680, AB-680, AB680, Inhibitor, inhibit

Similar Products

  • AB-680 ammonium [orb1983382]

    614.89

    C20H30ClFN6O9P2

    5 mg, 50 mg
  • AB-680 [orb1218463]

    >98% (HPLC)

    2105904-82-1

    580.83

    C20H24ClFN4O9P2

    1 g, 200 mg, 5 mg, 500 mg, 2 mg, 10 mg, 25 mg, 50 mg, 100 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

AB-680 (orb1310029)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 160.00
2 mg
$ 210.00
5 mg
$ 290.00
1 ml x 10 mM (in DMSO)
$ 360.00
10 mg
$ 440.00
25 mg
$ 700.00
50 mg
$ 980.00
100 mg
$ 1,310.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry