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A17

SKU: orb2564308

Description

A17 is a bile acid analog used in NASH research for its anti-inflammatory and anti-steatotic properties. It reduces fatty acid uptake via Cd36 suppression and promotes fatty acid oxidation through AMPKα activation, as demonstrated in in vitro and in vivo studies of metabolic liver disease.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation, Signal Transduction

Images & Validation

Key Properties

CAS Number2568186-47-8
MW533.74
FormulaC31H51NO6
SMILESO(C=O)[C@@H]1[C@@]2([C@@]([C@]3(C)[C@](C1)(C[C@H](OC=O)CC3)[H])(CC[C@@]4(C)[C@]2(CC[C@@]4([C@@H](CCC(N[C@@H](C(C)C)CO)=O)C)[H])[H])[H])[H]
TargetAMPK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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A17 (orb2564308)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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25 mg
$ 1,560.00
50 mg
$ 2,020.00
100 mg
$ 2,540.00
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