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A11

SKU: orb2563656

Description

A11 is an ANXA1-derived peptide that disrupts the ANXA1-EphA2 interaction, promoting Cbl-mediated EphA2 ubiquitination, internalization, and degradation. This mechanism inhibits proliferation, migration, invasion, and angiogenesis in nasopharyngeal carcinoma (NPC) cells, supporting its use in oncological research targeting the EphA2 signaling pathway.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

TargetEphrin Receptor,Annexin A
Molecular Weight1225.35

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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A11 (orb2563656)

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