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A011

SKU: orb2278463

Description

A011 is a potent and selective ATM kinase inhibitor with an IC50 of 1.0 nM. In research, it induces apoptosis and G2/M arrest when combined with CPT-11 (irinotecan), demonstrating antitumor efficacy in both cellular and in vivo models.

Research Area

Cell Biology, Molecular Biology, Signal Transduction

Images & Validation

Key Properties

MW452.55
FormulaC27H28N6O
TargetATM/ATR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information