8-Hydroxyoctanoic acid-thalidomide

SKU: orb2665471

Description

This conjugate, which combines an 8-hydroxyoctanoic acid linker with a thalidomide-based E3 ligase ligand, is a key chemical component for constructing PROTAC molecules like Lw13. It is used in biochemical research to study targeted protein degradation in both cellular and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2399454-65-8
• MW: 401.46
• Formula: C₂₁H₂₇N₃O₅
• SMILES: O=C(O)CCCCCCCNC1=CC=CC=2C(=O)N(CC12)C3C(=O)NC(=O)CC3
• Target: E3 Ligase Ligand-Linker Conjugates

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

150903709