7-Ketolithocholic acid

SKU: orb1308874

Description

7-Ketolithocholic acid is an absorbable bile acid derivative that inhibits endogenous bile acid synthesis and biliary cholesterol secretion. It is utilized in research exploring cholesterol metabolism, liver function, and as a modulator of nuclear receptors like FXR in both in vitro and in vivo models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 4651-67-6
• MW: 390.56
• Purity: 99.90%
• Formula: C₂₄H₃₈O₄
• SMILES: [H][C@@]12CC[C@H]([C@H](C)CCC(O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])C(=O)C[C@]2([H])C[C@H](O)CC[C@]12C
• Target: Endogenous Metabolite
• Solubility: DMSO:100 mg/mL (256.04 mM)

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cholesterol, 3a-Hydroxy-7-oxo-5b-cholanic acid, 3alpha-Hydroxy-7-oxo-5beta-cholanic acid, 3α-Hydroxy-7-oxo-5β-cholanic acid, 7Ketolithocholic acid, 7-Ketolithocholic acid, acid, 7 Ketolithocholic acid, biliary, bile, Inhibitor, inhibit, EndogenousMetabolite, Endogenous Metabolite, endogenous, Human Endogenous Metabolite, secretion

Compound Identifiers

PubChem CID

444262