5,7-Dichlorokynurenic acid

SKU: orb1305892

Description

5,7-Dichlorokynurenic acid sodium salt is a selective NMDA receptor antagonist acting at the glycine site. It is widely used in neuroscience research to study excitotoxicity, synaptic plasticity, and neurological disorders in both in vitro and in vivo experimental models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 131123-76-7
• MW: 258.06
• Purity: 99.71% (May vary between batches)
• Formula: C₁₀H₅Cl₂NO₃
• SMILES: OC(=O)c1cc(O)c2c(Cl)cc(Cl)cc2n1
• Target: NMDAR,iGluR
• Solubility: DMSO:55 mg/mL (213.13 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (9.69 mM);1eq. NaOH:100 mM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cortical cell, Competitive, 5,7 Dichlorokynurenic acid, 5,7-DCKA, 5,7Dichlorokynurenic acid, 5,7-Dichlorokynurenic acid, 5,7-dichlorokynurenic acid sodium, NMDA receptor, neuron injury, kynurenic acid, glycine site

Compound Identifiers

PubChem CID

1779