5,6-Dihydrothymidine

SKU: orb1907914

Description

2'-Deoxy-N2-methylguanosine is a modified nucleoside analog used as a biochemical tool to investigate DNA-protein interactions. It serves as a probe in both in vitro binding assays and in vivo studies to elucidate mechanisms in epigenetics and DNA repair research.

Research Area

Cell Biology, Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 5627-00-9
• MW: 244.24
• Formula: C₁₀H₁₆N₂O₅
• SMILES: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)CC(C)C(=O)N1
• Target: Others

Bioactivity

• In Vitro:
  5,6-Dihydrothymidine was studied in human liver microsomes to evaluate its potential toxicological risk as a food processing contaminant. 5,6-Dihydrothymidine was shown to undergo metabolism by cytochrome P450 enzymes in vitro and may contribute to DNA base oxidation damage.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

165328