5'-ODMT cEt G Phosphoramidite (Amidite)

SKU: orb1982701

Description

This phosphoramidite monomer is used to synthesize constrained ethyl (cEt)-modified antisense oligonucleotides. These analogs exhibit enhanced nuclease resistance and potent biological activity, making them valuable tools for both in vitro mechanistic studies and in vivo therapeutic research targeting gene expression.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 945628-66-0
• MW: 881.95
• Formula: C₄₆H₅₆N₇O₉P
• SMILES: [H][C@]12O[C@@H](C)[C@](COC(c3ccccc3)(c3ccc(OC)cc3)c3ccc(OC)cc3)(O[C@H]1n1cnc3c1[nH]c(NC(=O)C(C)C)nc3=O)[C@H]2OP(OCCC#N)N(C(C)C)C(C)C
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

135938544