5’-O-(4,4’-Dimethoxytrityl)-3’-O-methyluridine

SKU: orb1907627

Description

This 3'-O-methylated, 5'-DMT-protected uridine derivative is a key building block for oligonucleotide synthesis, where its ribose modification confers nuclease resistance. It is widely used in the development of antisense oligonucleotides and siRNAs for both in vitro biochemical studies and in vivo therapeutic research.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 127212-40-2
• MW: 560.59
• Formula: C₃₁H₃₂N₂O₈
• SMILES: C(OC[C@@H]1[C@@H](OC)[C@@H](O)[C@@H](O1)N2C(=O)NC(=O)C=C2)(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

23257699