5-(Methoxycarbonyl)methyluridine (MCM5U)

SKU: orb1908927

Description

5-(Methoxycarbonyl)methyluridine (mcm5U) is a critical tRNA modification found in yeast that ensures proper anticodon loop structure for mRNA codon binding. Its absence, such as in Elongator complex mutants like elp3, is linked to translational defects and increased protein aggregation, making it a key molecule for studying translation fidelity and proteostasis in vivo.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 29428-50-0
• MW: 316.26
• Formula: C₁₂H₁₆N₂O₈
• SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(CC(OC)=O)=C2
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

5-Methoxycarbonyl methyl uridine, 5-(Methoxycarbonyl)methyluridine (MCM5U)

Compound Identifiers

PubChem CID

3080753