5-Hydroxymethyl-2'-deoxycytidine

SKU: orb1690311

Description

5-Hydroxymethyl-2'-deoxycytidine (5-hmdC) is an oxidative DNA lesion derived from 5-methylcytosine, associated with genomic instability and PARP1-mediated replication fork stress. This product is used in epigenetics and DNA damage research to study its roles in cellular toxicity, chromosomal aberrations, and related in vitro and in vivo models.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 7226-77-9
• MW: 257.24
• Purity: 99.95%
• Formula: C₁₀H₁₅N₃O₅
• SMILES: Nc1nc(=O)n(cc1CO)[C@H]1C[C@H](O)[C@@H](CO)O1
• Target: DNA/RNA Synthesis,PARP
• Solubility: DMSO:45 mg/mL (174.93 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.77 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

5-Hydroxymethyl-2'-deoxycytidine, 5Hydroxymethyl2'deoxycytidine, 5hmdC, 5 Hydroxymethyl 2' deoxycytidine, PARP1

Compound Identifiers

PubChem CID

169016