5-Fluorouracil-13C,15N2

SKU: orb1693351

Description

This stable isotope-labeled analog of 5-fluorouracil serves as an internal standard for precise quantification via GC- or LC-MS. The parent drug is a cytotoxic pyrimidine analog that inhibits thymidylate synthase and incorporates into nucleic acids, disrupting DNA/RNA synthesis. It is widely used in cancer research for pharmacokinetic and metabolic studies in both cell-based and animal models.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 1189423-58-2
• MW: 133.057
• Formula: C₄H₃FN₂O₂
• SMILES: Fc1c[15nH][13c](=O)[15nH]c1=O
• Target: Endogenous Metabolite,Nucleoside Antimetabolite/Analog,HIV Protease,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

57369200