5’-DMTr-dC (Ac)-methylphosphonamidite

SKU: orb1907542

Description

This product is a methylphosphonamidite derivative of 5'-O-DMTr-2'-deoxycytidine, bearing an acetyl-protected exocyclic amine. It serves as a key phosphoramidite monomer for the solid-phase synthesis of methylphosphonate oligonucleotides, which are utilized in vitro for antisense research and as nuclease-resistant probes.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 178094-78-5
• MW: 716.8
• Formula: C₃₉H₄₉N₄O₇P
• SMILES: C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)C)C[C@@H](O1)N2C(=O)N=C(NC(C)=O)C=C2)(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11104516