5'-Amino-5'-deoxyadenosine

SKU: orb1705283

Description

5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor with demonstrated antitumor activity against lymphoid malignancies. Its anticancer effects, studied in vitro and in vivo, are primarily mediated through the inhibition of DNA synthesis and the induction of apoptotic cell death.

Research Area

Cell Biology, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 14365-44-7
• MW: 266.26
• Purity: 99.72% (May vary between batches)
• Formula: C₁₀H₁₄N₆O₃
• SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CN)[C@H]1O
• Target: Apoptosis,Nucleoside Antimetabolite/Analog,Adenosine Receptor
• Solubility: DMSO:50 mg/mL (187.79 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.51 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Nsc 238990, NH2dAdo, 5'-Amino-5'-deoxyadenosine, 5'Amino5'deoxyadenosine, 5' Amino 5' deoxyadenosine, Adenosine kinase, Adenosine Receptor, AdenosineReceptor, Apoptosis, DNA

Compound Identifiers

PubChem CID

9816781