4′-DTMP

SKU: orb1944603

Description

4′-Demethyltrimethoprim (4′-DTMP) is a potent inhibitor of E. coli dihydrofolate reductase (DHFR), exhibiting enhanced binding through additional local enzyme interactions. This small molecule is a valuable research tool for studying antibacterial mechanisms and DHFR function in both in vitro enzymatic assays and microbiological studies.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 21253-58-7
• MW: 276.29
• Formula: C₁₃H₁₆N₄O₃
• SMILES: OC1=C(OC)C=C(C=C1OC)CC2=CN=C(N=C2N)N
• Target: DHFR,Antifungal

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

10423570