4-Azido-L-homoalanine HCl (L-AHA)

SKU: orb65054

Description

4-Azido-L-homoalanine (L-AHA) provides a non-radioactive alter-native to analyze the global protein synthesis in cell culture. It is cell-permeable and randomly incorporated instead of methionine during translation. The resulting azide-labeled full-length pro-teins can subsequently be detected via Cu(I)-catalyzed or Cu(I)-free click chemistry that offers the choice to introduce a Biotin group (via Azides of Biotin or DBCO-containing Biotin, respectively) for subsequent purification tasks or a fluorescent group (via Azides of fluorescent dyes or DBCO-containing fluorescent dyes, respectively) for subsequent microscopic imaging.

Images & Validation

• Application Notes:
  Proteins synthesis monitoring.

Key Properties

• CAS Number: 942518-29-8
• MW: Theoretical MW: 144.13 g/mol; Detected MW: 144.06 g/mol
• Purity: mass identification conforms (ESI-MS)
• Formula: C₄H₈N₄O₂
• SMILES: OC(=O)[C@H](CCN=[N+]=[N-])N

Storage & Handling

• Storage: store at 4 C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

(S)-2-Amino-4-azidobutanoic acid hydrochloride

Compound Identifiers

PubChem CID

147480