4-(2-Azidoethyl)phenol

SKU: orb3028977

Description

4-(2-Azidoethyl)phenol is a bifunctional small molecule probe featuring both a phenolic hydroxyl group and an azide structure. Its core application lies in the phenol moiety serving as a substrate for APEX2 (ascorbate peroxidase), generating reactive radicals in situ in the presence of H₂O₂ to label neighboring proteins. Concurrently, the terminal azide group can be linked to alkyne-labeled detection molecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC) to achieve biotinylation or fluorescence visualization. 4-(2-Azidoethyl)phenol is widely used in proximity labeling-based proteomics research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: Others
• Molecular Weight: 163.18
• Purity: 98.86% (May vary between batches)
• CAS Number: 74447-34-0
• Formula: C₈H₉N₃O
• SMILES: [N-]=[N+]=NCCC1=CC=C(O)C=C1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others