3-Methyl-2-oxobutanoic acid

SKU: orb1301973

Description

3-Methyl-2-oxobutanoic acid (2-Oxoisovaleric acid) is a neurotoxic keto-acid metabolite from incomplete branched-chain amino acid catabolism, leading to organic acidemias. It is used in research models of maple syrup urine disease (MSUD) to study metabolic acidosis and neurotoxicity in vitro and in vivo.

Research Area

Metabolism Research

Key Properties

• CAS Number: 759-05-7
• MW: 116.12
• Purity: 98.00%
• Formula: C₅H₈O₃
• SMILES: CC(C)C(=O)C(O)=O
• Target: Endogenous Metabolite
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (17.22 mM);H2O:100 mg/mL (861.18 mM);DMSO:30 mg/mL (258.35 mM)

Storage & Handling

• Storage: Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, EndogenousMetabolite, Endogenous Metabolite, 3Methyl2oxobutanoic acid, 3-Methyl-2-oxobutanoic acid, 2-Oxoisovaleric acid, 3 Methyl 2 oxobutanoic acid, alpha-Ketoisovaleric acid, a-Ketoisovaleric acid, α-Ketoisovaleric acid

Compound Identifiers

PubChem CID

49