3’- Methoxy Puerarin

SKU: orb1220303

Description

3'-Methoxypuerarin shows neuron protection activity it can protect hippocampal neurons against ischemia/reperfusion injury by inhibiting apoptosis. 3'-Methoxypuerarin has antioxidant activities it shows ONOO(-) scavenging activity and weak NO· and O(2)(-) scavenging activities.

Key Properties

• CAS Number: 117047-07-1
• MW: 446.4
• Purity: >98% (HPLC)
• Formula: C₂₂H₂₂O₁₀
• SMILES: COc(cc(cc1)C2=COc(c([C@@H]([C@@H]([C@H]3O)O)O[C@H](CO)[C@H]3O)c(cc3)O)c3C2=O)c1O
• Target: Antioxidant
• Solubility: In Vitro: DMSO : 250 mg/mL (560.04 mM)

Bioactivity

• In Vivo:
  3'-Methoxypuerarin increases the number of surviving neurons in the hippocampal CA1 region and markedly reduces the number of apoptotic pyramidal neurons after ischemia/reperfusion injury. 3'-Methoxypuerarin can protect hippocampal neurons against I/R injury by inhibiting apoptosis.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Antioxidant