3-Deoxy-3-fluoro-D-fructose

SKU: orb3173317

Description

3-Deoxy-3-fluoro-D-fructose (Compound 12) is a derivative of 2,5-Anhydro-D-mannitol. It serves as a selective probe for hexose transporter 5 (GLUT5). This compound inhibits the transport of [14C]-labeled D-fructose by GLUT5, with IC50 values of 1.16 µM in EMT-6 cells and 2.37 µM in MCF-7 cells. Additionally, 3-Deoxy-3-fluoro-D-fructose is useful for positron emission tomography (PET) imaging in cancer studies.

Key Properties

• CAS Number: 110925-86-5
• MW: 182.15
• Formula: C₆H₁₁FO₅
• SMILES: [C@H]([C@@H]([C@@H](CO)O)O)(C(CO)=O)F
• Target: transporter

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

transporter