22-Hydroxy mifepristone

SKU: orb2802190

Description

22-Hydroxy Mifepristone (RU 42698) is an orally active metabolite with anti-progestational and anti-glucocorticoid activity, exhibiting 48% relative binding affinity to the human glucocorticoid receptor. Its alkyne group enables CuAAC click chemistry conjugation, facilitating its use as a probe in receptor binding studies and mechanistic research both in vitro and in vivo.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 105012-15-5
• MW: 445.59
• Formula: C₂₉H₃₅NO₃
• SMILES: C[C@@]12[C@]([C@]3(C([C@H](C1)C4=CC=C(N(C)C)C=C4)=C5C(CC3)=CC(=O)CC5)[H])(CC[C@]2(C#CCO)O)[H]
• Target: Endogenous Metabolite,Glucocorticoid Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

13605512