2'-OMe-Ac-C Phosphoramidite

SKU: orb1982156

Description

This modified phosphoramidite is a key reagent for the solid-phase synthesis of 2'-O-methylated oligonucleotides. Such synthetic oligonucleotides are widely used in vitro and in vivo for applications in antisense research, siRNA therapeutics, and molecular diagnostics due to their enhanced nuclease resistance and binding affinity.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 199593-09-4
• MW: 801.86
• Formula: C₄₂H₅₂N₅O₉P
• SMILES: CO[C@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)O[C@H]1n1ccc(NC(C)=O)nc1=O
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

70700567