2'-O-Methylinosine

SKU: orb1908961

Description

2'-O-Methylinosine is a synthetic purine nucleoside analog known for its oral bioavailability and antihypertensive properties. It serves as a research tool in cardiovascular studies, with applications in both in vitro enzymatic assays and in vivo models of hypertension.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 3881-21-8
• MW: 282.25
• Formula: C₁₁H₁₄N₄O₅
• SMILES: O(C)[C@H]1[C@H](N2C3=C(N=C2)C(=O)N=CN3)O[C@H](CO)[C@H]1O
• Target: Others
• Solubility: DMSO:80 mg/mL (283.44 mM)

Bioactivity

• In Vivo:
  2'-O-Methylinosine (100 mg/kg, ip) has a significant antihypertensive effect in rats.
• In Vitro:
  2'-O-Methylinosine effectively inhibits FrC6 virus reverse transcriptase activity in cell-free systems.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

2'-(o-Methyl)-inosine

Compound Identifiers

PubChem CID

135412763