2-O-Ethyl PAF C-16

SKU: orb2283617

Description

2-O-Ethyl PAF C-16 is a structural analog and competitive antagonist of Platelet-Activating Factor (PAF) at its receptor (PAFR). It demonstrates potent binding inhibition, displacing the PAF antagonist WEB 2086 with an IC50 of 21 nM. This compound is a valuable tool for investigating PAFR signaling in inflammation, allergy, and shock research using both cellular and animal models.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 78858-42-1
• MW: 509.709
• Formula: C₂₆H₅₆NO₆P
• SMILES: CCCCCCCCCCCCCCCCOC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OCC
• Target: Others,PAFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

24779410