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2-Methoxyestradiol (Standard)

SKU: orb3141073

Description

2-Methoxyestradiol (Standard) is a reference standard for research and analysis in studies involving 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endothelial cell apoptosis. This agent also inhibits tumor cell growth by binding to tubulin, resulting in antimitotic activity, and by inducing caspase activation, resulting in cell cycle arrest in the G2 phase, DNA fragmentation, and apoptosis.

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Key Properties

CAS Number362-07-2
MW302.41
FormulaC19H26O3
SMILES[H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3cc(OC)c(O)cc3CC[C@@]21[H]
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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2-Methoxyestradiol (Standard) (orb3141073)

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