2-Methoxyestradiol-13C6

SKU: orb3138432

Description

2-Methoxyestradiol-13C6 is a 13C-labeled version of 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2) is an orally active endogenous metabolite of 17β-estradiol (E2) that functions as an apoptosis inducer and an angiogenesis inhibitor with significant antitumor activity. It also disrupts the stability of microtubules. Furthermore, 2-Methoxyestradiol is a potent inhibitor of superoxide dismutase (SOD) and a promoter of reactive oxygen species generation, inducing autophagy in transformed cell line HEK293, and cancer cell lines U87 and HeLa.

Key Properties

• Target: Autophagy,Microtubule Associated,Endogenous Metabolite,Reactive Oxygen Species,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Autophagy,Microtubule Associated,Endogenous Metabolite,Reactive Oxygen Species,Apoptosis