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2'-Deoxycytidine monohydrate

SKU: orb1221408

Description

One of the principal nucleosides of DNA composed of cytosine and deoxyribose. A nucleoside consists of only a pentose sugar linked to a purine or pyrimidine base without a phosphate group. When N1 is linked to the C1 of deoxyribose deoxynucleosides and nucleotides are formed from cytosine and deoxyribose; deoxycytidine monophosphate (dCMP) deoxycytidine diphosphate (dCDP) deoxycytidine triphosphate (dCTP). CTP is the source of the cytidine in RNA (ribonucleic acid) and deoxycytidine triphosphate (dCTP) is the source of the deoxycytidine in DNA (deoxyribonucleic acid).

Images & Validation

Key Properties

CAS Number951-77-9
MW227.22
Purity>98% (HPLC)
FormulaC9H13N3O4
SMILESNc1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1
TargetEndogenous Metabolite
SolubilityDMSO: 10 mM;Water:50mg/mL

Bioactivity

In Vivo
Animal model: Mice inoculated SP2/0 myeloma cells. Dosage: 25 mg/kg. Administration: i. v. , 4 times, from 8 days to 16 days. Result: Decreased the tumor weight and volume. Increased survival time.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Cytosine deoxyriboside | Deoxycytidine | Deoxyribose cytidine | 2'-Deoxycytidine | Cytosine deoxyribonucleoside | 2(1H)-Pyrimidinone
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Protocol Information

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100 mg
$ 80.00
500 mg
$ 160.00