2-Aminofluorene

SKU: orb1940454

Description

2-Aminofluorene is a biochemical.

Key Properties

• CAS Number: 153-78-6
• MW: 181.238
• Purity: >98% (HPLC)
• Formula: C₁₃H₁₁N
• SMILES: Nc1ccc-2c(Cc3ccccc-23)c1
• Solubility: In Vitro: DMSO : 100 mg/mL (551.75 mM)

Bioactivity

• In Vivo:
  2-Aminofluorene (60 mg/kg, i.p.) accumulates twice the 2-Aminofluorene-DNA adducts of slow acetylators (A/J) in rapid acetylator mice (C57BL/6J). 2-Aminofluorene (60 mg/kg, i.p.) forms significantly higher levels of DNA adducts in tumor-target organs than in non-target organs in acetylator congenic hamsters.
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• In Vitro:
  2-Aminofluorene (0-100 μM, 1-5 days) produces a dose-related suppression of the antibody response to sheep erythrocytes (SRBC), DNP-Ficoll, and LPS.2-Aminofluorene (0-100 μM, 3 days, spleen cells) produces suppression on lymphoproliferative responses to LPS and Con A.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

2-Aminofluorene | 2-Fluorenamine