(1S,3R)-GNE-502

SKU: orb1686996

Description

(1S,3R)-GNE-502 is a potent and selective ERα degrader, demonstrating in vitro efficacy in MCF7 breast cancer cells with an EC50 of 13 nM. This small molecule is a valuable research tool for investigating estrogen receptor biology and therapeutic strategies in ER-positive cancers.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1953134-15-0
• MW: 471.59
• Formula: C₂₅H₃₀FN₃O₃S
• SMILES: S(C)(=O)(=O)N1[C@H](C2=C(C=3C(N2)=CC=CC3)C[C@H]1C)C4=CC=C(OCCN5CC(CF)C5)C=C4
• Target: Others,Estrogen Receptor/ERR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

121410755