1,4-Diaminobutane Dihydrochloride

SKU: orb1704866

Description

1,4-Diaminobutane dihydrochloride exhibits antidepressant and analgesic properties in biomedical research. In plant science, it functions as a dual-action agent, directly inhibiting fungal pathogens like Colletotrichum gloeosporioides and inducing systemic resistance, thereby enhancing post-harvest disease resistance in fruits such as mango.

Research Area

Metabolism Research

Key Properties

• CAS Number: 333-93-7
• MW: 161.07
• Purity: 99.88%
• Formula: C₄H₁₄Cl₂N₂
• SMILES: NCCCCN.Cl.Cl
• Target: Endogenous Metabolite
• Solubility: DMSO:5 mg/mL (31.04 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (6.21 mM);H2O:40 mg/mL (248.34 mM)

Bioactivity

• In Vivo:
  Administration of 1, 4-diaminobutane Dihydrochloride in mice exacerbated colon inflammation and increased intestinal permeability. 1,4-Diaminobutane Dihydrochloride (1% concentration added to drinking water) reduces EcNC101 colonization and tumor development in AOM/DSS mouse models of colorectal cancer.
• In Vitro:
  1,4-Diaminobutane Dihydrochloride (100-1000 μM, 24 h) stimulated the growth of CT-26 tumor cells. 1,4-Diaminobutane Dihydrochloride (33.2 mmol/L, 24h) disrupted epithelial compact junction (TJ) integrity in isolated mouse colon tissue. 1,4-Diaminobutane Dihydrochloride (0.25-1 mmol/L) significantly reduced bacterial growth in a concentration-dependent manner.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

1,4Diaminobutane Dihydrochloride, 1,4-Diaminobutane Dihydrochloride, 1,4-Diaminobutane, 1,4-butanediamine Dihydrochloride, 1,4 Diaminobutane Dihydrochloride, Putrescine

Compound Identifiers

PubChem CID

9532